My dad had skin grafts on his leg during the 70s. The technology wasn't great and the skin barely took. He keeps getting blood infections because he needs to exercise for blood to circulate correctly and he takes shit care of himself and refuses.
So he just lays around as his legs literally die and infect the rest of his body. This is his third time in the hospital in two years. He's going to kill himself and he doesn't give a shit.